The triangles represent the histological spectrum in the hyaline vascular and plasma cell variants of CD. Percentages for some CD subtypes are not available. CD, Castleman disease; HHV8, human ...

Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the ...

Researchers headed by a team at Seattle Children’s Research Institute have shown for the first time that engineered human plasma B cells can be used to treat a disease—more specifically leukemia—in a ...

Many symptoms of multiple myeloma (MM) overlap with other conditions, including low back pain, diabetes, chronic kidney disease and arthritis. Renal insufficiency caused by MM can be difficult to ...

Castleman disease (CD) is a rare, non-clonal lymphoproliferative disorder that manifests with a wide range of histologic and clinical features. It is classified clinically into unicentric (UCD) and ...

Inflammatory molecules circulating in the blood may worsen disease symptoms and points to new opportunities for targeted ...